20 years of toxicology.
نویسنده
چکیده
With over 80,000 chemicals being used in commerce worldwide, it is important to identify the human health effects of these chemicals and the levels of exposure at which they are harmful to humans. In order to address this need, the National Toxicology Program (NTP) was established in 1978; since then, the NTP has become the world's leader in designing, conducting, and interpreting various types of toxicity assays.
منابع مشابه
Epidemiological Study of Patients Poisoned by Poisonous Plants in Isfahan
Background and purpose: Nowadays, plants are more available and many are used for treatment purposes, therefore, the rate of poisoning by plants has increased. According to the geographical location of Isfahan in Iran, the present study aimed at investigating this problem since there is paucity of information about plant poisoning in the region. Materials and methods: In this cross-sectiona...
متن کاملAlternative methods in toxicology: pre-validated and validated methods
The development of alternative methods to animal experimentation has progressed rapidly over the last 20 years. Today, in vitro and in silico methods have an important role in the hazard identification and assessment of toxicology profile of compounds. Advanced alternative methods and their combinations are also used for safety assessment of final products. Several alternative methods, which we...
متن کاملCytochrome p450 and chemical toxicology.
The field of cytochrome P450 (P450) research has developed considerably over the past 20 years, and many important papers on the roles of P450s in chemical toxicology have appeared in Chemical Research in Toxicology. Today, our basic understanding of many of the human P450s is relatively well-established, in terms of the details of the individual genes, sequences, and basic catalytic mechanisms...
متن کاملThe Frequency of the Causes of Acid Base Disturbances in Patients Hospitalized in the Toxicology Ward of Baharloo Hospital in 2009
Background: The aim of this study was to evaluate the efficacy of arterial blood gases (ABGs) in determining the type of intoxication. Methods: Medical charts of all patients who had referred to the toxicology ward of Baharloo Hospital between January 2009 and December 2009 were evaluated. After excluding the patients with multi-drug toxicity, data, including age, sex, type of intoxication ...
متن کاملFish models in behavioral toxicology: Automated techniques, updates and perspectives
Introduction Since the science of toxicology began thousands of years ago, behavioral endpoints have been used to study the effects of chemicals and drugs on humans and other mammals. In aquatic toxicology however, the nexus of behavioral sciences with the study of toxicants has only become prominent within the last 5 decades. Behavioral endpoints have been slow to be integrated in aquatic toxi...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- Environmental Health Perspectives
دوره 106 شماره
صفحات -
تاریخ انتشار 1998